Injectable Gel Could Spell Relief For Arthritis Sufferers

Main Category: Arthritis / Rheumatology
Also Included In: Pain / Anesthetics
Article Date: 13 Apr 2011 – 4:00 PDT

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Some 25 million people in the United States alone suffer from rheumatoid arthritis or its cousin osteoarthritis, diseases characterized by often debilitating pain in the joints. Now researchers at Brigham and Women’s Hospital (BWH) report an injectable gel that could spell the future for treating these diseases and others.

New Therapy Shows Novel Therapeutic Approach To Fighting Inflammation

Main Category: Immune System / Vaccines
Also Included In: Arthritis / Rheumatology
Article Date: 08 Apr 2011 – 0:00 PDT

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Researchers at Charite Universitatsmedizin Berlin have succeeded in finding a new therapeutic approach to certain inflammatory reactions of the body. The focus of this new approach, developed under the leadership of Prof. Dr. Schwab, are known as guidance molecules, which reduce the body’s own immune system to the required level and prevent excessive and damaging inflammation. Possible applications include therapies for inflammation, such as blood poisoning, but also in chronic inflammation and immunological inflammations such as rheumatoid arthritis and organ rejection.

Chemical Engineers At UCSB Design Molecular Probe To Study Disease

Main Category: Medical Devices / Diagnostics
Also Included In: Cancer / Oncology;  Alzheimer’s / Dementia;  Arthritis / Rheumatology
Article Date: 07 Apr 2011 – 5:00 PDT

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Chemical engineers at UC Santa Barbara expect that their new process to create molecular probes may eventually result in the development of new drugs to treat cancer and other illnesses.

Their work, reported in the journal Chemistry Biology, published by Cell Press, describes a new strategy to build molecular probes to visualize, measure, and learn about the activities of enzymes, called proteases, on the surface of cancer cells.

Absorption Of Curcuminoids Increased 29-Fold With Meriva(R)

Main Category: Complementary Medicine / Alternative Medicine
Also Included In: Arthritis / Rheumatology;  Bones / Orthopedics;  Pain / Anesthetics
Article Date: 06 Apr 2011 – 8:00 PDT

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In a new comparative absorption study[1] published in the Journal of Natural Products Meriva®, an Indena proprietary formulation of curcumin with soy lecithin, has shown a marked increase of absorption in comparison to plain curcumin.

Personalised Therapies For Inflammation Created By Researchers Able To Mimic Body’s Own Healing Potential

Main Category: Immune System / Vaccines
Also Included In: Heart Disease;  Arthritis / Rheumatology
Article Date: 05 Apr 2011 – 4:00 PDT

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Scientists at Barts and The London School of Medicine and Dentistry and Harvard Medical School, Boston have found a way of mimicking the body’s natural mechanism of fighting inflammation. During inflammation cells release very small particles termed ‘microparticles’ that retain features of their parent cell. The scientists discovered that certain microparticles were beneficial to health, and that these microparticles contained anti-inflammatory lipids, which help terminate inflammation and return the body to its normal balance.

TxCell Receives Approval For A Phase I/II Clinical Trial In Rheumatoid Arthritis

Main Category: Arthritis / Rheumatology
Also Included In: Clinical Trials / Drug Trials
Article Date: 04 Apr 2011 – 4:00 PDT

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TxCell SA, a biotechnology company developing cell-based immunotherapies for the treatment of severe chronic inflammatory diseases with high unmet medical need, announces today the approval by AFSSAPS, the French regulatory agency, of its application to carry out a phase I/II clinical trial of its second product candidate, TX-RAD.

AIDS Virus Blocked From Entering Cells By Engineered Protein Fragment

Main Category: HIV / AIDS
Also Included In: Immune System / Vaccines;  Arthritis / Rheumatology;  Lupus
Article Date: 01 Apr 2011 – 2:00 PDT

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In what could be a potential breakthrough in the battle against AIDS and a major development in the rational design of new drugs, scientists have engineered a new protein that prevents the virus from entering cells. This protein is based on a naturally occurring protein in the body that protects cells from viruses, except the man-made version does not cause inflammation and other side effects at the dosages needed to inhibit AIDS. This discovery was published in the April 2011 issue of The FASEB Journal.

New Clinical Practice Guidelines Developed For Juvenile Idiopathic Arthritis

Main Category: Arthritis / Rheumatology
Also Included In: Pediatrics / Children’s Health
Article Date: 31 Mar 2011 – 0:00 PDT

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The American College of Rheumatology has developed new guidelines for starting and monitoring treatments for children with juvenile idiopathic arthritis. These are the first JIA guidelines endorsed by the ACR, with the goal of broad acceptance within the rheumatology community.

Created as a guide for health care providers, the guidelines focus on the initiation and safety monitoring of multiple medications used in the treatment of JIA, including:

Osteoarthritis: What You Know Could Save Your Joints!

Main Category: Arthritis / Rheumatology
Also Included In: Bones / Orthopedics;  Rehabilitation / Physical Therapy
Article Date: 31 Mar 2011 – 3:00 PDT

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According to the Arthritis Foundation, 27 million Americans live with osteoarthritis, the most common form of arthritis which involves a mechanical “wear and tear” of the cartilage that lines the inside of our joints and which, over time, can result in damage to the connective tissue and bone around the joint. The more you know about the condition, the greater your chance for success in finding the help that you need.

Experts Exchange Information And Updates On Spondyloarthritis

Main Category: Arthritis / Rheumatology
Also Included In: Bones / Orthopedics
Article Date: 30 Mar 2011 – 0:00 PDT

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Spondyloarthritis (SpA) is a group of inflammatory conditions causing spine and joint pain and deformity, mostly in young men. Important updates on the epidemiology, diagnosis, and treatment of SpA are presented in the April issue of The American Journal of the Medical Sciences (AJMS), official journal of the Southern Society for Clinical Investigation. The journal is published by Lippincott Williams Wilkins, a part of Wolters Kluwer Health.