About one third of those who suffer from psoriasis develop inflammation in their joints (psoriatic arthritis) as a result of the chronic skin condition. A research team has now discovered a key starting point for inhibiting inflammation in both psoriasis and psoriatic arthritis. The researchers’ findings may form the basis for developing new treatment, diagnostic and prevention strategies.
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A new study reveals that walking for exercise can reduce new frequent knee pain among people age 50 and older diagnosed with knee osteoarthritis, the most common form of arthritis. Additionally, findings from the study indicate that walking for exercise may be an effective treatment to slow the damage that occurs within the joint.
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New research has shown that molecular profiling of the diseased joint tissue can significantly impact whether specific drug treatments will work to treat rheumatoid arthritis (RA) patients. The researchers also identified specific genes associated with resistance to most available drugs therapies, commonly referred to as refractory disease, which could provide the key to developing new, successful drugs to help these people.
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Adenosine triphosphate (ATP) secreted from sensory neuron-interneuron crosstalk is key to the spreading of inflammation across joints, acting as a neurotransmitter and inflammation enhancer.
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New research has identified a crucial link between arthritis and the risk of serious liver disease in people with hemochromatosis.
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Researchers evaluated the ability of a polygenic risk score constructed from a genome-wide association study of rheumatoid arthritis susceptibility to predict radiographic progression, which is indicative of structural joint damage in individuals with rheumatoid arthritis. The research team identified an association between the polygenic risk score and radiographic progression, an observation that was pronounced in people with a younger age of onset of rheumatoid arthritis.
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An international research team has established a link between gut microbiota and chronic inflammatory diseases such as arthritis. The team has discovered that a protein naturally present in the gut acts on the microbiota and causes the formation of molecules that exacerbate the symptoms of these diseases.
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Researchers have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress the activity of these cells, increasing vulnerability to infection.
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Researchers have discovered that having one kind of autoimmune disease can lead to another.
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A new study shows an increased risk of patients developing illnesses including mental ill-health and heart conditions if they have a GP-inputted medical history of gum disease.
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