New research has identified a crucial link between arthritis and the risk of serious liver disease in people with hemochromatosis.
Visit the Source Site
Powered by WPeMatico
New research has identified a crucial link between arthritis and the risk of serious liver disease in people with hemochromatosis.
Visit the Source Site
Powered by WPeMatico
Researchers evaluated the ability of a polygenic risk score constructed from a genome-wide association study of rheumatoid arthritis susceptibility to predict radiographic progression, which is indicative of structural joint damage in individuals with rheumatoid arthritis. The research team identified an association between the polygenic risk score and radiographic progression, an observation that was pronounced in people with a younger age of onset of rheumatoid arthritis.
Visit the Source Site
Powered by WPeMatico
An international research team has established a link between gut microbiota and chronic inflammatory diseases such as arthritis. The team has discovered that a protein naturally present in the gut acts on the microbiota and causes the formation of molecules that exacerbate the symptoms of these diseases.
Visit the Source Site
Powered by WPeMatico
Researchers have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress the activity of these cells, increasing vulnerability to infection.
Visit the Source Site
Powered by WPeMatico
Researchers have discovered that having one kind of autoimmune disease can lead to another.
Visit the Source Site
Powered by WPeMatico
A new study shows an increased risk of patients developing illnesses including mental ill-health and heart conditions if they have a GP-inputted medical history of gum disease.
Visit the Source Site
Powered by WPeMatico
Researchers used gallic acid, an antioxidant found in gallnuts, green tea and other plants, and applied a stretching mechanism to human cartilage cells taken from arthritic knees that mimics the stretching that occurs when walking. The combination not only decreased arthritis inflammation markers in the cells but improved the production of desired proteins normally found in healthy cartilage. While still at an early stage, the findings suggest a new procedure could be developed to treat cartilage cells extracted from a patient to grow a supply of cells or a tissue to be re-implanted.
Visit the Source Site
Powered by WPeMatico
Exercise increases the body’s own cannabis-like substances, which in turn helps reduce inflammation and could potentially help treat certain conditions such as arthritis, cancer and heart disease.
Visit the Source Site
Powered by WPeMatico
New data shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages. Danger signals released by damaged cells during inflammation play a role during this process. ‘Rewiring’ the mitochondria in the macrophages protects them against overloading and can thus improve the way in which parts of damaged cells are eliminated and resolve the inflammatory reaction.
Visit the Source Site
Powered by WPeMatico
Researchers have made a discovery that could lead to new treatments for axial spondyloarthritis (SpA), a painful and debilitating form of arthritis which causes inflammation in the spine, joints, eyes, gut and skin.
Visit the Source Site
Powered by WPeMatico