Arthritis News – Latest Medical News

Crucial link found between arthritis, liver disease and a common genetic condition

New research has identified a crucial link between arthritis and the risk of serious liver disease in people with hemochromatosis.
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Predicting the progression of rheumatoid arthritis

Researchers evaluated the ability of a polygenic risk score constructed from a genome-wide association study of rheumatoid arthritis susceptibility to predict radiographic progression, which is indicative of structural joint damage in individuals with rheumatoid arthritis. The research team identified an association between the polygenic risk score and radiographic progression, an observation that was pronounced in people with a younger age of onset of rheumatoid arthritis.
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Scientists discover link between gut microbiota and chronic inflammatory diseases like arthritis

An international research team has established a link between gut microbiota and chronic inflammatory diseases such as arthritis. The team has discovered that a protein naturally present in the gut acts on the microbiota and causes the formation of molecules that exacerbate the symptoms of these diseases.
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How oral bacteria suppress protection against viral growth

Researchers have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress the activity of these cells, increasing vulnerability to infection.
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One autoimmune disease could lead to another

Researchers have discovered that having one kind of autoimmune disease can lead to another.
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Gum disease increases risk of other illness such as mental health and heart conditions, study suggests

A new study shows an increased risk of patients developing illnesses including mental ill-health and heart conditions if they have a GP-inputted medical history of gum disease.
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Gallic acid and stretching decrease osteoarthritis markers in cartilage cells

Researchers used gallic acid, an antioxidant found in gallnuts, green tea and other plants, and applied a stretching mechanism to human cartilage cells taken from arthritic knees that mimics the stretching that occurs when walking. The combination not only decreased arthritis inflammation markers in the cells but improved the production of desired proteins normally found in healthy cartilage. While still at an early stage, the findings suggest a new procedure could be developed to treat cartilage cells extracted from a patient to grow a supply of cells or a tissue to be re-implanted.
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Exercise increases the body’s own ‘cannabis-like’ substance which reduces chronic inflammation

Exercise increases the body’s own cannabis-like substances, which in turn helps reduce inflammation and could potentially help treat certain conditions such as arthritis, cancer and heart disease.
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When macrophages let off steam

New data shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages. Danger signals released by damaged cells during inflammation play a role during this process. ‘Rewiring’ the mitochondria in the macrophages protects them against overloading and can thus improve the way in which parts of damaged cells are eliminated and resolve the inflammatory reaction.
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Potential new therapy for inflammatory arthritis

Researchers have made a discovery that could lead to new treatments for axial spondyloarthritis (SpA), a painful and debilitating form of arthritis which causes inflammation in the spine, joints, eyes, gut and skin.
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