Predicting the progression of rheumatoid arthritis

Researchers evaluated the ability of a polygenic risk score constructed from a genome-wide association study of rheumatoid arthritis susceptibility to predict radiographic progression, which is indicative of structural joint damage in individuals with rheumatoid arthritis. The research team identified an association between the polygenic risk score and radiographic progression, an observation that was pronounced in people with a younger age of onset of rheumatoid arthritis.
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