Knee and Hip Replacements May Be Bad for the Heart

Contrary to recent reports, researchers found that osteoarthritis patients who had total knee or hip joint replacement surgery, known as arthroplasty, were at increased risk of heart attack (myocardial infarction) in the early post-operative period. However, findings indicate that long-term risk of heart attack did not persist, while the risk for venous thromboembolism — blood clot in veins and lungs — remained years after the procedure.
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Adverse effects of common prostate enlargement and hair growth drugs

Twenty-five percent of men currently taking Finasteride or Dutasteride, popularly known as Proscar and Avodart, for the treatment of benign prostate enlargement, appear not to benefit from taking these medications. Those prescribed Propecia or Avodart for male pattern hair loss (known as alopecia) are also at risk for adverse events elicited by these drugs.
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How newts can help osteoarthritis patients

Osteoarthritis is the most common form of joint disease worldwide. Now, scientists have taken a leaf out of nature’s book in an attempt to develop effective stem cell treatment for osteoarthritis, a condition which affects millions of people in the UK alone.
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Newborn care inspection announced

Newborn care in England under inspection

  • 20 August 2015
  • From the section Health
Neonatal care involves the care of babies born early and those needing treatment at the start of life

Neonatal services within and outside hospitals will be examined

A review of the care available to newborns and young babies with severe health problems has been announced by the Care Quality Commission.

It will draw on the case of Elizabeth Dixon, from Surrey, who died 14 years ago after a breathing tube was not dealt with correctly.

The CQC says it wants to identify what barriers can stop hospitals from providing good or outstanding care.

Stroke 'more likely' with long hours

Stroke ‘more likely’ with long hours

By James Gallagher
Health editor, BBC News website
  • 20 August 2015
  • From the section Health
Woman working

People working long hours are more likely to have a stroke, according to analysis of more than half a million people.

The data, published in the Lancet medical journal, showed the chance of a stroke increased beyond the traditional 9am to 5pm.

The link is uncertain, but theories include a stressful job and the damaging impact on lifestyle.

Experts said people working long hours should monitor their blood pressure

Extra virgin olive oil linked to lower blood sugar and cholesterol


(Reuters Health) – Compared to other kinds of fat, extra virgin olive oil may have healthier effects on levels of blood sugar and bad cholesterol after meals, according to an Italian study.

That may explain why a traditional Mediterranean diet rich in olive oil is linked to lower risk of cardiovascular disease, researchers say.

“Lowering (post-meal) blood glucose and cholesterol may be useful to reduce the negative effects of glucose and cholesterol on the cardiovascular system,” lead study author Francesco Violi, a researcher at Sapienza University in Rome, said by email.

Lilly, Boehringer diabetes drug cuts heart attack, stroke risk in trial


A new diabetes pill from Eli Lilly and Co and Boehringer Ingelheim cut risk of heart attack, stroke and death in a closely watched study, the first glucose-lowering drug to show such protective results in a large cardiovascular trial, the drugmakers said on Thursday.

Besides burnishing the image of the year-old drug, Jardiance, the results could raise the profile of rival new drugs in the same class of medicines called SGLT2 inhibitors, such as Johnson & Johnson’s Invokana and AstraZeneca Plc’s Farxiga.

Morning Break: Pelvic Mesh Scandal, Off-Label No-Nos

“In the little known world of medical lending, financiers invest in operations to remove pelvic implants from women suing device makers – and reap an inflated share of the payouts when cases settle,” Reuters reports in an eye-opening story.

StemExpress, the firm that worked with Planned Parenthood patients to facilitate medical uses of fetal tissue, has ended its relationship with the women’s health organization to escape the political firestorm. (Los Angeles Times)

GOP lawmakers are asking the Justice Department to provide information on laws banning for-profit sale of fetal tissue, and to report on their “history of enforcement” of those laws, according to CBS News.

Hospira announces TGA approval of Inflectra (infliximab) for treatment of eight inflammatory conditions

Hospira today announced that InflectraTM (infliximab), the first monoclonal antibody (mAb) biosimilar therapy, has been registered in Australia. This registration paves the way for the Federal Government to reduce the cost of some of the most expensive medicines on the Pharmaceutical Benefits Scheme (PBS).

Inflectra has been registered in Australia for the treatment of eight inflammatory conditions: rheumatoid arthritis (RA); psoriatic arthritis; ankylosing spondylitis (AS); adult and paediatric Crohn’s disease; refractory fistulising Crohn’s disease; adult and paediatric ulcerative colitis; and plaque psoriasis.

Inflectra is a biosimilar medicine formulated to deliver comparable efficacy, safety and quality as the originator biologic, Remicade® (infliximab) – a mAb therapy that cost the PBS more than $100 million last year.

NHS 'could prescribe E-cigarettes'

E-cigarettes could be prescribed by the NHS to help smokers quit, report says

By Adam Brimelow
Health correspondent, BBC News
  • 19 August 2015
  • From the section Health
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Woman smoking an electronic cigarette

E-cigarettes are 95% less harmful than tobacco and could be prescribed on the NHS in future to help smokers quit, a review of their use has concluded.

Experts who have compiled a report for Public Health England say “vaping” could be a “game changer” for persuading people to quit cigarettes.

They also say there is no evidence they give children a “gateway” into smoking.